Isekai animes have more freedom than their non-isekai counterparts. By taking their main characters out of the real world and placing them in a fantasy world, thebest isekai anime seriescan operate using their own rules. That means protagonists can live in worlds with magic, granting them abilities their previous worlds never could have. Characters like Tanya van Degurechaff fromThe Saga of Tanya the Evilwere normal people in their past lives. In their new lives, however, they’re powerful characters capable of devastating powers.
Isekai protagonists are usually granted a special power when they enter their new worlds as well, making their fights even more exciting.No matter what ability is being put on display, a good isekai fight can rival thebest fights in anime.They can also set the tone for the show their in, letting everyone know just how intense things can get.

That Time I Got Reincarnated as a Slimefeatures one of the deepest and richest worlds in isekai anime. The world Rimuru Tempest has found himself in is complicated, to say the least. In Rimuru’s world, there’s a power hierarchy led by the Demon Lords at the very top.Two of the strongest beings in the world, Milim Nava the Destroyer and Carrion the Beastmaster, have a fight that shakes that power structure to its core.
Milim Nava is the strongest woman inThat Time I Got Reincarnated as a Slimeand may just be the strongest character outright.As the daughter of Veldanava, the world’s creator, she has access to True Dragon Magic Carrion can only dream of. While Carrion transforms into his glorious Royal Beast Form, he’s no match for the Dragonoid Milim. She uses her Drago Nova on Carrion, and while barely missing him, destroys most of his nation and a giant mountain in the process.

9Tanya vs. Anson - The Saga of Tanya the Evil
Magical Gunfire Never Looked This Good
The Saga of Tanya the Evilstars one of the cutest and deadliest isekai protagonists there could be. Tanya van Degurechaff is a 12-year-old military leader, an expert on the battlefield, and a cold-blooded killer all at once.Her battle against Anson and his troops in the skies above the desert wasTanyaat its best.Tanya darts away from her allies and into her enemies. She fires bullets all around, hitting her opponents in flashes of blue and purple. Anson comes with a special shotgun that blows Tanya and her allies out of the sky.
Tanya recovers and dashes at her opponent with her knife in hand. She’s able to stab Anson before its revealed that Being X is possessing him. Being X latches onto Tanya before self-destructing. Unfortunately for Being X,Tanya’s friends arrive in time to save her, allowing her to create some space between herself and Anson before littering his body with bullets.
8Rimuru vs. The Kingdom of Falmuth - That Time I Got Reincarnated as a Slime
The Most One-Sided Battle The Slime Has Fought
Rimuru Tempest has never really been one for battle. He’ll fight to defend his friends, but that’s about it.When Shion is found dead, all bets are off.Rimuru finds the invading Falmuth warriors and casts one of the most one-sided spells in anime. Rimuru flies into the air high above the soldiers and casts Megiddo. The magic works by creating small water droplets in the air that then reflect beams of light. Those beams of light are then focused into laser beams and sent through the heads of Rimuru’s enemies.
The attack is incredibly effective as the attack itself doesn’t use magicules, natural energy, or anything other than sunlight itself to kill its opponents. Megiddo wiped Falmuth off the map before they could ride into battle. Rimuru then used the souls of the people he had just killed to transform into a Demon Lord, gaining even more power for his enemies to fear.
Mushoku Tensei: Jobless Reincarnationis an anime well known for itstop-tier art and animation, rich world, and great cast of characters. It’s not a show known for its fights, which makes Rudeus, Eris, and Rujierd vs. Orsted that much better. As Dead End is traveling back home, they come across the Dragon God himself. Rujierd and Eris are in complete fear of Orsted because of his innate ability, but Rudeus isn’t.Because he isn’t scared like his companions, Orsted knows that he knows Hitogami, the Man God and Orsted’s enemy.
Orsted rushes at the trio and takes on Rujierd first. Rujierd had been unstoppable up until this point in the series, but Orsted makes him look like an amateur. After tossing aside the Supierd like he was nothing, Orsted kills Rudeus and tells him to let the Man God know he’s coming.
Shadow is by far the strongest person in all ofThe Eminence in Shadow.He’s so strong that he’s pretty bored most of the time and is more than happy to fight anyone who can challenge him.He couldn’t have been happier when Aurora, the Witch of Calamity, was summoned to be his opponent in the Sanctuary. She is the main antagonist of the new world he’s been isekai’d into and one of the few people that can keep up with Shadow.
Their fight is gorgeous.They weave back and forth like ballroom dancers, each participant smiling from ear to ear.When the time comes to end the fight, Shadow remarks that he’s happy to have faced Aurora but disappointed that he couldn’t fight her at full strength. He zooms through her Blood Magic before defeating her with a single sword slash. They both finish the fight smiling.
5Lloyd vs. Guisarme - I Was Reincarnated as the 7th Prince So I Can Take My Time Perfecting My Magical Ability
I Was Reincarnated as the 7th Princefeatures great action sequenceswith complex yet understandable spells. Lloyd loves learning new spells and is constantly looking for someone strong enough to try them on. While most characters in the series aren’t even strong enough to make Lloyd sweat, the demon lord Guisarme was. He took over Jade’s body to use Jade’s incredible teleportation technique and fought Lloyd effectively. While Guisarme certainly put up a good fight, Lloyd’s passion for magic was too much for him.
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Lloyd learned how to dodge Guisarme’s fatal Shadow Wolf ability right as he saw it. It’s ironic that Lloyd was bored after fighting Guisarme for a couple of minutes because the fight was anything but.Lloyd ends the showdown by using Guisarme’s strongest ability, the Mortal Dark Sphere, against him effortlessly.
4Garfiel vs. Elsa - Re:Zero - Starting Life in Another World
Garfiel Joining Subaru’s Side Paid Off
Re:Zero - Starting Life in Another Worldis another isekai anime that isn’t well-known for its fights. When it does have fights, however, the stakes are high, the action is palpable, and someone is more than likely going to die. Elsa is one of the scariest characters in all ofRe:Zero.She’s a sociopath at the very least, taking a lot of pleasure in hurting other people. She was actually the first person to kill Subaru way back in season one and hasn’t stopped her killing spree since.
She’s back to kill the main cast of characters, but this time, Garfiel is there to defend them. He does an excellent job of doing so, fighting the assassin in fierce combat before eventually killing her for good.His fight is brutal, bloody, and everything else that could come from a series as twisted asRe:Zero.
3Shadow vs. Beatrix and Iris - The Eminence in Shadow
Even Two-On-One, Shadow Didn’t Break a Sweat
Shadow’s fight vs. Beatrix and Iris wasn’t much of a fight. Instead, Shadow entertained the two girls until he got bored, but it was entertaining for a while. The trio danced around the city as Beatrix and Iris used everything they had against Shadow. Their sword skills weren’t bad, but it wasn’t anything concerning for the leader of Shadow Garden. After fighting the pair for a little bit, Shadow is ready to end it. He sits the girls down, points his sword in the air, and shrouds the entire city in a dark purple light.
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The girls are petrified. They think Shadow is going to obliterate their city. Instead, Shadow says he’s going Atomic and simply disappears.It’s a funny ending to one of the best fights in the series and leaves Beatrix and Iris feeling silly for thinking they even had a chance.
Overlord
Cast
Overlord follows a salaryman who, after being trapped in a virtual reality game, assumes the role of an all-powerful skeletal overlord. As he navigates this new world filled with magic and mythical creatures, he seeks to understand the game’s mysteries and conquer its challenges. The series blends elements of fantasy and adventure, exploring themes of power and identity.
Overlorddoes a great job of showing what a fight in an MMO would look like in anime format. Ainz Ooal Gown is the leader of the Great Tomb of Nazarick, the most powerful organization in the world. One of his strongest warriors, Shalltear Bloodfallen, has fallen under the control of outside influences and is looking to fight. Ainz finds her on the battlefield in full armor and gets ready to battle.Before he fights her, however, he casts dozens of buffs on himself like a true MMO player would.
WhileAinz is one of the most powerful beings in isekai history, he doesn’t want to kill Shalltear. He knows how valuable she is and realizes that she’s probably under some sort of mind control at this point. After getting all of his buffs ready, Ainz uses his Super-Tier spell, Fallen Dawn, to level the battlefield and set the tone right away.
1Makoto vs. Sofia and Lancer - Tsukimichi: Moonlit Fantasy
Makoto Let Loose For The First Time and the World Felt It
Makoto Misumi got the short end of the stick when he was isekai’d into his new world. The Goddess didn’t like him because she thought he was ugly and banished him to the wastelands of the continent. Luckily for Makoto, he was able to find amazing friends to support him when the Goddess didn’t. Unfortunately, this wasn’t the only time Makoto suffered because of the Goddess. Later in the series, Lancer and Sofia ambush Makoto after he is transported by the Goddess against his will. Not only does the Goddess land him in hot water, but Lancer and Sofia fight him because they think he’s fightingon herbehalf.
They’re able to sever two of Makoto’s fingers, making the World Traveler furious. He decides to let loose and breaks several of his Draupnir rings, filling himself with power. Makoto then flies into the air, launching an incredibly powerful arrow at his enemies. The arrow connects, severing one of Lancer’s legs and obliterating Sofia’s armor.It’s one of the most refreshing moments of paybackTsukimichi,or any isekai, has to offer.