Scrubshad several guest stars that varied in their level of fame, but if the show’s revival plans pay off, the return of one minor side character from the original run would be completely different from their debut back in 2003. Although theScrubsrevivalhasn’t been confirmed, those associated with the medical sitcom have been incredibly vocal about its imminent comeback.Showrunner Bill Lawrence has gone as far as to say that it’s “definitely going to” happen. So, it just seems like a matter of time at this point before JD and company are back on TV.
Throughoutall nine seasons ofScrubs, guest stars played a big part in the sitcom’s success. For instance,Michael J. Fox’sScrubsseason 3 episodesare still renowned as some of the show’s best efforts. Some temporary cast members left a bigger mark than others, but their fame at the time of their episodes wasn’t always a factor in how effective they were. For one star in particular, they have since become a household name. However,they weren’t quite as well-known when they were onScrubs.

Ryan Reynolds Returning As Spence In Scrubs' Revival Would Be Nothing Like “My Dream Job”
Spence’s lone appearance came in the Scrubs season 2 finale
It seems strange to remember a time when Ryan Reynolds wasn’t solidly in the public eye, but that was the case when he played Spence inScrubsseason 2, episode 22, “My Dream Job.” Although the success of 2002’sVan Wilder: Party Liaisonhad boosted Reynolds' profile somewhat, he was still very far from the superstar status he has since achieved.Reynolds' role in “My Dream Job” is incredibly limited, and he isn’t given all that much to do. While he plays the part well, Spence is fairly forgettable andScrubsdoesn’t make much of a fuss about casting Reynolds.
Scrubs Season 10 Must Bring Back This Vital Side Character Who Only Appeared In 16 Episodes
Scrubs' revival will make a little less sense if one side character from the original run doesn’t return, even if their presence was quite brief.
When the sitcom returns,another Ryan Reynolds appearance would be impossible to ignore. The writers would be far more likely to give him a much more prominent role in the episode, with Spence essentially taking center stage throughout. He would arguably overshadow the entire installment, which wouldn’t be unreasonable given how famous he’s become since his firstScrubsappearance. From a story standpoint, a Spence comeback would probably be pretty low on the list of priorities forScrubsseason 10, but the fact that he’s played by Ryan Reynolds drastically alters the appeal.

Could Scrubs Get Ryan Reynolds Back As Spence?
Reynolds' immense star power could make him difficult to cast in Scrubs season 10
Although Reynolds began his acting career by splitting his time between TV shows and movies, the former is very rare for him these days. There’s also the consideration that he’s now so sought after due to the success of theDeadpoolmovies,Scrubsmay not be able to afford to pay him. On the other hand, his strong connection to Disney and the MCU may work ever so slightly in the sitcom’s favor, asScrubsis also the property of the same studio. That being said, it’s still difficult to imagine Reynolds showing up inScrubsagain, no matter how great it would be.
Scrubs
Cast
Scrubs is a Sitcom and Medical Comedy/Drama created by Bill Lawrence that follows a group of medical students throughout their daily lives at the Sacred Heart Teaching Hospital. The series stars Zach Braff, Sarah Chalke, and Donald Faison, as they work their way up from Medical Interns while juggling all sorts of hospital shenanigans.
